Summaries by Inventor Hallahan, Dennis

Antibodies to MDK
Hallahan, Dennis ; Kapoor, Vaishali
T-018978

— MDK is a molecular target for treatment of cancer. These antibodies are to the functional domain of MDK.

Anti-PDZ TIP1 Antibody Therapy for Cancer
Hallahan, Dennis ; Kapoor, Vaishali ; Yan, Heping
T-017064

— Background: Lung cancer is one of the leading causes of cancer-related deaths worldwide. In the United States, it is second most common cancer for men and women and the leader for cancer-related death. Non-small-cell lung cancer (NSCLC) accounts for 85% of all reported lung cancer cases and is relat…

PEGylated-GIRLRG Peptide for Radiopharmaceutical Delivery
Hallahan, Dennis
T-014562

— Technology: GRP78 is a chaperone that is part of a complex that controls the maturation of glycoproteins in the ER and senses cellular stress in normal cells. However, following radiation treatment, GRP78 is also expressed on the surface of cancer cells and has anti-apoptotic and pro-angiogenesis ac…